• CICRA commits a further £425,000 for research into Inflammatory Bowel Disease

    Following our yearly round of applications for funding we are pleased to announce additions to our research programme covering three funding streams.

    After going through a rigorous peer review process using external referees the following recommendations were made to the Trustees by the Awards Advisory Panel.

    DNAA Research Fellowship was awarded to Professor Ian Sanderson for Dr Protima Amon at Bart’s and the Royal London Hospital.  As Professor Sanderson is the Chairman of the Advisory Panel he took no part in the Peer Review for this funding stream and we were very grateful to Dr Christine Spray, Consultant Paediatric Gastroenterologist at Bristol Children’s Hospital and Dr Jonathan Hind, Consultant Gastroenterologist at University College Hospital, London who, as completely independent advisors, joined the interviewing panel.  We thank our advisors for giving their time to help us fund only worthwhile research.

    Protima AmonDr Protima Amon will be working on an innovative project looking at how the trillions of bacteria of over 1000 different types may be affected by the enteral diet.  If an improvement in the condition of the gut is found to be associated with changes in the bacteria, the medical professionals can aim to maintain the composition of bacteria to achieve long term health in children with Crohn’s disease.

    A PhD studentship was awarded to Professor Wileman of the Norwich Medical School at the University of East Anglia.  This studentship will commence in September and Professor Wileman will be looking to appoint a suitable candidate during the next few months.  The appointed student will be carrying out a genetic study and depending on the results this may open up the possibility of personalized medicine for children with Crohn’s disease who carry a specific gene.

    Neil McCarthyFunding of a one year project was approved by the Trustees for Dr Neil McCarthy , an immunologist at the Centre for Digestive Diseases, at the Blizard Institute, London.  Having recently shown that PAg-activated delta2 cells in human blood can travel to the intestine and increase the inflammatory activity of other cell types in the gut Dr McCarthy will now aim to investigate the biological role and potential therapeutic targeting of these cells in Crohn’s Disease.

    Jenny Epstein 2009 - Research FellowDr Jenny Epstein, a former CICRA Research Fellow, now a Consultant at the Chelsea & Westminster Hospital has been looking at bacteria living in and on us (the human microbiome) which play an important role in human health and disease.  A project grant was award to Jenny to further this work where she is seeking answers to several questions including:  How does the microbiome change with diet in Crohn’s disease?

    We wish our researchers every success in their studies to help children, young people and indeed everybody  with Inflammatory Bowel Disease.